Disease surveillance and outbreak prevention and control pdf, 58kb chapter 7. There has been considerable debate regarding the value of both the 1997 and 2009 world health organization who dengue case classification criteria for its diagnosis and management. Clinical manifestations and management of denguedhfdss. Thrombocytopenia and hemoconcentration are distinguishing features between dhfdss and dengue fever df. Burke, evidence that maternal dengue antibodies are important in the development of dengue hemorrhagic fever in infants, american journal of tropical medicine and hygiene, vol. In 2004, of 3186 cases of dengue fever df hemorrhagic dengue fever dhf admitted to our institution, there were cases of dhf and seven dengue associated deaths casefatality rate 5. Review of dengue hemorrhagic fever fatal cases seen among. At least three of the seven fatal cases had serological evidence of primary dengue infection. Dengue is a febrile illness caused by a flavivirus transmitted by aedes aegypti or aedes albopictus mosquitoes while taking a blood meal. Caused by one of four closely related virus serotypes of the genus flavivirus, family flaviviridae, each serotype is sufficiently different that there is no crossprotection and epidemics caused by multiple serotypes hyperendemicity can occur.
Pdf prevalence of dengue fever during 2011 2012 in punjab. Dengue fever this article was prepared to provide more information about dengue fever and dengue hemorrhagic fever dengue fever warning an april 2011 news article cautioned that the medical sciences national institute of health had warned that this years weather changes could lead to an outbreak of dengue fever. Symptoms include frontal headache, retroorbital pain, myalgias, arthralgias, hemorrhagic manifestations, rash, and. Current and historical conditions indexed list of current and historical nationally notifiable conditions. Infection with one serotype of denv provides immunity to that. A subgroup analysis in a study conducted in thailand revealed that 18. Primary infection usually results in milder illness, while more severe disease occurs in cases of repeated infection with different serotypes. To provide a national incidence rate and case fatality rate of dengue hemorrhagic fever in indonesia through an analysis of the national disease surveillance database from the directorate general of disease prevention and control of ministry of health. Dengue hemorrhagic fever and shock syndromes article in pediatric critical care medicine 121.
Epidemiology of dengue hemorrhagic fever in indonesia. Mortality rate of patients with dengue hemorrhagic fever. Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of climate. Figure 4 dengue and dengue hemorrhagic fever, brazil, 1981.
Fatal dengue hemorrhagic fever in adults during a dengue. Dengue hemorrhagic fever sweden pdf ppt case reports. Author summary dengue continues to be a major mosquitoborne disease of serious public health concern. Countries or territories in which dengue or dengue haemorrhagic fever is known to occur, by who region, 19751996 pdf, 26kb annex 2.
Health experts have known about dengue fever for more than 200 years. Yellow fever differential diagnoses medscape reference. Number of dengue feverrelated hospitalizations per state by year, brazil, 19902003. Prevalence of dengue fever during 2011 2012 in punjab. We did not observe a difference in the severity of dhf between the patients with primary and secondary infections. Each dot represents the number of hospitalizations due to denguedengue hemorrhagic fever for 1 state by year. Radiological appearance and their significance in the. Dengue fever dengue hemorrhagic fever dengue fever dengue hemorrhagic fever bruce r. Thailand reported the worst dengue virus outbreak in 20 years, with 126 deaths and 5,344 people infected with the virus, in october 20. Dengue hemorrhagic fever can occur when someone is bitten by a mosquito or exposed to blood infected with the dengue virus. Dengue hemorrhagic fever frequently requires prior infection with the dengue virus. Centers for disease control and prevention clinical diagnosis dengue classic dengue fever, or break bone fever, is characterized by acute onset of high fever 314 days after the bite of an infected mosquito.
To demonstrate various imaging features of dhf and their significance for the. Patients with dhfdss have fever, hemorrhagic manifestations along with thrombocytopenia and hemoconcentration. Dengue hemorrhagic fever and shock syndromes request pdf. As the disease spreads to new geographical areas, the frequency of the outbreaks is increasing. Dengue fever symptoms, causes, contagious, rash, prevention. Children are usually the most affected group, but in recent decades, dengue and severe dengue have become more common among adults. Once you are infected with one of the dengue viruses, you will develop immunity to that. Hospitalization information systemunified health system sihsus. Dengue fever is a mosquitoborne viral illness found throughout the. New world or tacaribe complex guanarito virus, junin virus, machupo virus, sabia virus. Mar 15, 2016 dengue hemorrhagic fever case study 1.
The aim of the study was to determine the mortality rate in dengue patients. Gubler division of vectorborne infectious diseases national center for infectious diseases centers for disease control and prevention public health service u. Dengue infectious diseases merck manuals professional edition. Dengue fever df is the fastest emerging arboviral infection spread by aedes aegypti mosquitoes with major public health consequences for millions of people around the world, and in particular the southeast asia and asiapacific regions of the world. Dengue hemorrhagic fever with dengue shock syndrome is a variant presentation that occurs primarily in children dengue is endemic. Dengue fever this article was prepared to provide more. Dengue fever breakbone, dengue hemorrhagic fever dengue fever is a mosquitoborne disease caused by one type of dengue virus. Clinical practice guidelines of denguedengue hemorrhagic. Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. There are four dengue virus denv types denv1, denv2, denv3, and denv4, all of which are capable of inducing severe disease dengue hemorrhagic fever dhf dengue shock syndrome dss. Department of health and human services po box 2087, fort collins, co 80522.
Pdf dengue fever outbreak in mogadishu, somalia 2011. Pathogenesis of dengue haemorrhagic fever and its impact on. Major research to cure the disease various researches includes means of vector control, vaccine development, and antiviral drugs are going on in sweden. Incorporating the revised dengue guidelines in general.
Dengue virus is found in many tropical parts of the world including the caribbean, central and south america, asia and africa. Severe dengue, dengue hemorrhagic fever dhf and dengue shock syndrome dss are accompanied by thrombocytopenia, vascular leakage and hypotension. Dec 22, 2011 the symptomatic cases are categorized as undifferentiated febrile illness uf, dengue fever df, dengue hemorrhagic fever dhf, dengue shock syndrome dss and unusual dengue ud or expanded dengue syndrome eds. To study the clinical spectrum of dengue hemorrhagic fever dhf and dengue shock. Call 7182221065 for more info on finding solutions for dengue hemorrhagic fever. Dengue fever in a patient recovering from coronary artery bypass. The classical form, dengue fever df, is characterized by high fever, headache, stomach ache, rash, myalgia and arthralgia. Dengue and dengue hemorrhagic fever 1 dengue and dengue hemorrhagic fever information for health care practitioners dengue is a mosquitoborne disease caused by any one of four closely related dengue viruses denv1, 2, 3, and 4. Todays topics arboviruses general concept dengue fever and dengue hemorrhagic fever mcqs and case studies 3. Department of health and human services centers for. Survey of crimeancongo hemorrhagic fever enzootic focus. Overview dengue is a mosquitoborne disease cause by any one of four closely related dengue viruses denv 1,2,3 and 4. Read more about symptoms, diagnosis, treatment, complications, causes and prognosis. Dengue is a febrile illness that can have a fatal outcome in severe cases.
It is a caused by a flavivirus with four distinct serotypes dv1, dv2, dv3, and dv4. Hemorrhagic tendencies evidenced by at least one of the following. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Only treatment is to treat the symptoms, helping body to heal naturally. Characterization of dengue virus isolates from patients. Pdf on sep 1, 2011, muhammad zaman khan assir and others published guidelines for clinical case management of dengue fever dengue hemorrhagic fever dengue shock syndrome 2011 in pakistan. The image below depicts palatal petechiae and hemorrhage in a patient with ebola virus disease evd.
Comprehensive guidelines for prevention and control of dengue and dengue hemorrhagic fever. A total of 1% of these persons are given a diagnosis of dengue hemorrhagic fever dhf and of these persons, the disease causes death in approximately 4% of the cases. If left untreated, dengue fever can develop into the fatal dengue hemorrhagic fever dhf. Dengue is a mosquitoborne disease caused by one of the four serotypes of dengue viruses. Who, comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever, 2011. In this paper clinical manifestations and management of dengue dhfdss are summarized.
Guerdan, md, mph abstract in september 2009 the first documented, locally acquired cases of dengue fever in eighty years were diagnosed in individuals living in or visiting key west, florida. Evaluation of the spatial risk factors for high incidence of. Jun 21, 2019 other viral hemorrhagic fevers with dengue and crimeancongo hemorrhagic fever being the most similar in presentation also remain among the differential diagnoses for severe yellow fever during the intoxication period and are important to consider, as they require unique isolation precautions. The disease is caused by dengue viruses that have four serotypes. Symptoms typically begin three to fourteen days after infection. Infection with one serotype of denv provides immunity to that serotype for life, but provides no longterm immunity to other serotypes.
During 20112015, we conducted a crimeancongo hemorrhagic fever virus cchfv survey in captured ticks that were feeding mainly on. Dengue fever is a mosquitoborne tropical disease caused by the dengue virus. The emergence of a global health problem dengue and dengue hemorrhagic fever dhf are caused by one of four closely related, but antigenically distinct, virus serotypes den1, den2, den3, and den4, of the genus flavivirus 1. Dengue hemorrhagic fever may arise from repeated infection with different serotypes of the dengue virus. Dengue hemorrhagic fever is caused by a virus for which there is no known cure or vaccine. Dengue virus infection may remain asymptomatic or manifest as nonspecific viral infection to life threatening dengue hemorrhagic fever dhf dengue shock syndrome dss. Hemorrhagic fevers viral page 1 of 7 hemorrhagic fevers viral table of contents overview about viral hemorrhagic fevers vhf cdc webpage vhf about diseasespecific viral hemorrhagic fever cdc webpage arenaviridae. A global public health problem in the 21st century by duane j. Differentiation between classic dengue fever df and dengue haemorrhagic fever dhf or severe dengue is a key aspect of dengue case classification. This disease used to be called breakbone fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Dengue fever dengue hemorrhagic fever dengue hemorrhagic fever dhf the following must all be present. Viral hemorrhagic fever dengue fever presented by jega subramaniam, student guided by ap. Texas has the highest number of cases of dengue fever in the united states.
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